The Merchant (Harvey Keitel) is a Westerner. A merchant dealing in precious stones from Afganistan and Turkey. He's above suspicion. In truth, the "Stone Merchant" is a Christian convert into Islam. He's rich, cultured, fascinating. Leda (Jane March) is a successful woman who works as Head of the Public Relations for a big company. She's married to Alceo, a professor at the Sapienza University, specialized in the history of terrorist movements. Alceo is on a wheel chair. He lost his legs in the attack to the American Embassy in Nairobi in 1998. Shahid is a terrorist. Now he's planning an attack along the English Channel. Their lives, their destinies cross in Turkey, where Leda and Alceo are on holiday. And the plot will go on to Rome and Turin till the epilogue of the attack on the ferry boat.

Giuseppe Moscati, Doctor saint of Naples, was a doctor of the early twentieth century, from an aristocratic family devoted his career to serving the poor. The film focuses on the human side, partially leaving aside the spiritual part.