Jimmy Neutron is the smartest kid in town. As a genius, Jimmy thinks most things can be solved with the invention of a new gizmo. But Jimmy usually takes the easy way out, and his backfiring gadgets result in comedic adventures.

Jimmy Neutron is a boy genius and way ahead of his friends, but when it comes to being cool, he's a little behind. All until one day when his parents, and parents all over Earth are kidnapped by aliens, it's up to him to lead all the children of the world to rescue their parents.