Geeky 14-year old Ethan is left to babysit his younger sister, Jane, with his best friend Benny but after Ethan inadvertently puts Jane in harm's way, his parents hire a professional babysitter, the beautiful yet mysterious 17-year-old Sarah who, unbeknownst to them, is actually a fledgling vampire.

An American man unwittingly gets involved with werewolves who have developed a serum allowing them to transform at will.

A company that produces a toxic chemical tries to improve its image via a popular spokesperson, Ricky Coogan. Ricky travels to South America to get a first-hand look at the chemical's effects and finds himself at a mutant freak farm. Elijah, who runs the farm, is only too happy to have new subjects on which to try his freak machine. The very chemical that Ricky is supposed to promote is the one responsible for creating the great variety of freaks.