The men of a small town on the edge of nowhere mysteriously disappear, one by one, leaving women and children behind to fend for themselves in a desolate and dreamlike world.

“Lies in Plain Sight” tells the story of Eva and her blind cousin Sofia (Martha Higareda), who were inseparable as children, with Eva the loyal companion who helped Sofia through her tough adolescent years. When Eva suddenly commits suicide, Sofia rushes home to her father, Hector (Benito Martinez), and Eva’s parents, Marisol (Rosie Perez) and Rafael (Yul Vásquez), to find answers. But the more she delves into Eva’s life, questioning her past boyfriends Ethan (Chad Michael Murray) and Christian (Christoph Sanders), the more Sofia realizes that their childhood was actually filled with dark, disturbing secrets.

High school student Jane Shipley seeks to mend her splintering relationship with childhood best friend Merritt, and fit in with her rebellious peers. When Jane's math teacher oversteps his bounds, an apathetic high school administration forces Jane and Merritt to take matters into their own hands, driving their relationship into further turmoil and inciting deadly consequences.