Seven women decide to fight the local drug cartel. When Las Vegas pop singer Michelle's brother is found severely beaten, he's discovered to have been on illegal drugs. Michelle meets with April, her brother's teacher, who reveals that she's secretly been gathering intelligence on the cartel's local processing plant, and Michelle agrees to help April with a plan to destroy the plant. With Michelle's fame opening the door, they recruit four more women with special skills and connections to help them carry out their audacious goal.

The Satans, a sadistic biker gang led by Anchor, go to a diner in the middle of the California desert where they terrorize owner Lew, waitress Tracy, and the patrons. One patron manages to escape, and must reach a town before the Satans catch up to and kill them.

Due to his violent past, Deputy Sheriff Thomas Jefferson Geronimo III has been transferred to a rural outpost. When two thugs kill the sheriff, Geronimo shoots one, and the other vows revenge. The thug turns out to be a mob boss, and the court orders Geronimo to extradite him back to Sicily. When their plane is hijacked, the adversaries find their roles reversed.

The janitor at a local high school is actually the scout for a coven of Satanists on the lookout for a virgin to sacrifice. One day he kidnaps the cheerleading squad to use for their rituals. However, unbeknownst to the devil-worshipers, one of the cheerleaders is actually a witch, and has plans of her own for the Satanists.