In the Olden Tymes, Count Regula is drawn and quartered for killing twelve virgins in his dungeon torture chamber. Thirty-five years later, he comes back to seek revenge on the daughter of his intended thirteenth victim and the son of his prosecutor in order to attain immortal life.

In his remote jungle hideout, the evil Fu Manchu and his sadistic daughter Lin Tang have discovered a deadly venom that affects only men. Using mind control Fu Manchu recruits six women to become carriers of the 'kiss of death' targeting key people of political influence. This will prevent them from interfering with his own ambition to spread his venomous death around the World's major cities in a plan to gain World domination.