Western sheriff Bob Wells is preparing to marry Sally Morgan; she loves part-Indian Wanenis, whose race is an obstacle. Sally flees the wedding with hypochondriac Henry Williams, who thinks he's just giving her a ride; but she left a note saying they've eloped! Chasing them are jilted Bob, Henry's nurse Mary (who's been trying to seduce him) and others.

A kind-hearted young man is thrown out of his corrupt home town of West Rome, Oklahoma. He falls asleep and dreams that he is back in the days of olden Rome, where he gets mixed up with court intrigue and a murder plot against the Emperor.