Nothing in the world can make Garfield get involved in anything besides eating, until the muscular super cat Garzooka comes crashing into Cartoon World from the Comic Book universe with terrifying news. Garfield summons up the willpower to join his superhero Garzooka in a fight to save their worlds.

Garfield and his owner, Jon Arbuckle, are in a rut. Life for them is a complete bore. They both need a life. Jon tries several unsuccessful times to get a date. Then he attends a class for the personality impaired where he meets a young woman and all seems to be great for Jon, but Garfield starts to feel neglected and left out.