An overgrown field and a stretch of highway connect a series of grisly murders spanning several decades as grieving families search for answers.

On another planet which resembles the Old West, a die-hard pacifist is forced to re-examine his ways after an evil alien bandit and his gang murder his estranged sheriff father, take over his home town, and threaten his friends.

Casey Anthony: An American Murder Mystery meets with the family at the center of it all, the Anthonys, to hear their first-hand account of the tragic details surrounding the death of their granddaughter, Caylee. We'll reveal the details surrounding the troubled investigation and explore new revelations in the case that outraged the nation.