Captain George Bryan Brummell is a British soldier who appreciates fine clothing and innovative dress. Although he initially alienates the Prince of Wales with insulting comments about the prince's uniform designs, he eventually becomes his close confidant. Brummel also falls in love with the beautiful Lady Patricia Belham. However, his outspoken manner eventually leads to his being exiled to France.

An American reporter in Japan is sent to interview an eccentric Japanese scientist working on bizarre experiments in his mountain laboratory. When the doctor realizes that the hapless correspondent is the perfect subject for his next experiment, he drugs the unfortunate man and injects him with a serum that gradually transforms him into a hideous, two-headed monster.