Den City is a city with advanced network systems in which a VR space called LINK VRAINS was created by SOL Technologies. The Knights of Hanoi, a group that hacks through dueling, as well as SOL Technologies are seeking a mysterious AI program. Yusaku Fujiki, also known as Playmaker, is a first year high school student who manages to capture this AI program while trying to find out the truth about an incident in the past.

Mitsuki Aya has one goal at the elite Kuromi Girls’ Academy: to become a refined young lady like the school’s flawless “White Lily,” Yorue Mio. But her image of Mio shatters when Aya accidentally catches her...playing fighting games?! Turns out, the elegant Mio is actually a hardcore gamer—and she wants to duel Aya! The battle (and their friendship) begins.

High school student Michio Kaga was wandering aimlessly through life and the Internet, when he finds himself transported from a shady website to a fantasy world — reborn as a strong man who can use "cheat" powers. He uses his powers to become an adventurer, earn money, and get the right to claim girls that have idol-level beauty to form his very own harem.

During her spring break at the end of her first year of high school, Ito's mother remarries, and Ito Hazui moves to live with her new family, becoming Ito Narita. Upon arriving at her new house, Ito is shocked to learn she now has four younger step-brothers. Ito tries her hardest to get along with all of the new members of her family, but the eldest brother Gen is a bit cold to her. However, under his aloof facade, he occasionally shows his kindness.