A small Army patrol unit and a couple of former Confederates reluctantly throw in their lot together after being attacked by a band of Native Americans.

The murders of two American plantation owners leads an Interpol agent into a battle with Filipino drug smugglers and violent religious fanatics.

A mad scientist, Dr. Aranya (Jackie Coogan), has created giant spiders in his Mexican lab in Zarpa Mesa to create a race of superwomen by injecting spiders with human pituitary growth hormones. Women develop miraculous regenerative powers, but men mutate into disfigured dwarves. Spiders grow to human size and intelligence.