Andrea (Riccardo Maria Manera) is a young man who lives with the surprises and hardships of life. He lives with his best friend, seeks to complete his studies and has an ex-girlfriend who plays with him like cat and mouse. When he discovers that he has an incurable disease, the world collapses on him. Can an illness change a person's life... for the better? Thanks to Giulia (Jenny De Nucci), Andrea will understand that the time has come to assume what remains of her own existence.

In 1913, laconic sea captain Corto Maltese, adrift in the Pacific, gets rescued by his bandit friend Rasputin who's taking two rich shipwrecked teens to an island where his boss the Monk will hold them for ransom. WWI complicates things.