The puppets battle their most powerful enemy yet as they protect their new master from the demon God that created the Secret of Life.@

Bud and Doyle are two losers who are doing nothing with their lives. Both of their girlfriends are actively involved in saving the environment, but the two friends couldn't care less about saving the Earth. One day, when a group of scientists begin a mission to live inside a "Bio-Dome" for a year without outside contact, Bud and Doyle mistakenly become part of the project themselves.

Van Wilder has been attending college for far too many years and is scared to graduate, but Van’s father eventually realizes what is going on. When he stops paying his son's tuition fees, Van must come up with the money if he wants to stay in college, so he and his friends come up with a great fund-raising idea – throwing parties. However, when the college magazine finds out and reporter, Gwen is sent to do a story on Van Wilder, things get a little complicated.

After his precocious behavior has gotten him bounced out of one more in a string of exclusive private schools, 16-year old Sebastian Valmont has arrived in New York City to live with his father and stepmother. The cunning and handsome Sebastian may have met his match, however in his equally manipulative and beautiful stepsister Kathryn Merteuil.

Francis and Blake Falls are Siamese twins who live in a neat little room in a rundown hotel. While sharing some organs, Blake is always fit and Francis is very sickly. Into their world comes a young lady, who turns their world upside down. She gets involved with Blake, and convinces the two to attend a Halloween party, where they can pass themselves off as wearing a costume. Eventually Francis becomes really ill, and they have to be separated. They then face the physical and mental strains that come from their proposed separation.