Ellie Carter is recently graduated and has it all. While celebrating with friend and boyfriend, she comes across a milk carton with a picture of a missing child that looks a lot like her. As a prank, they call the toll free number and she realizes that this person could be her. The more she finds out, the closer she gets to getting herself and beloved ones killed.

La Ciudad de las Estrellas, a tiny town in the South American jungle, is home to an understaffed, understocked medical clinic where three idealistic doctors come looking for change.

John Vandermark (Cumming) has taken in a struggling writer, Sebastian St. Germain (Boreanaz), who overstays his welcome. When John discovers that Sebastian has simply been using him, he turns the tables on his young tenant in an effort to make him work off his rent debt. When Sebastian dies accidentally in the process, John tries to make it up to him by helping him get his book published posthumously. When the book is published, John can't help but take credit for the work of genius... and Sebastian comes back to haunt him.

American science-fiction drama television series