A young woman wanders around New York City and stumbles across a number of strange characters and settings that represent the "underground" areas of the city. She sees stand up comedy in Central Park, a prostitution auction, a voodoo ceremony, an S&M club, and a number of very interesting performance artists. These are just a few of the sights and sounds of New York that she encounters.

Toxie finds he has nothing to do as a superhero, as he has ridden his city of evil. He decides to go to work for a major corporation, which he discovers may be the evilest of all his adversaries.

The Toxic Avenger is tricked into traveling to Tokyo to search for his estranged father, leaving Tromaville open to complete domination by an evil corporation.