Ten years after the original Robocop, Delta City is city owned and operated by OCP. RoboCop finds himself nearly obsolete and his former partner, John Cable, has returned to Delta City as its new Security Commander. But slowly, new enemies arise, and Murphy and Cable begin an investigation into a mysterious villain known as the Bone Machine.

The four turtles travel back in time to the days of the legendary and deadly samurai in ancient Japan, where they train to perfect the art of becoming one. The turtles also assist a small village in an uprising.