As four lifelong friends, Will, Bryan, Matt, and Corey, are on the road trip they've been planning their whole lives, Corey's beloved grandfather unexpectedly dies. When going to claim Corey's inheritance, the gang meets Matt's beautiful cousin Jessie and embark on a hilarious, extreme sports-filled adventure.

Interviews with scientists and authors, animated bits, and a storyline involving a deaf photographer are used in this docudrama to illustrate the link between quantum mechanics, neurobiology, human consciousness and day-to-day reality.