On a Tuesday night, five couples have separate sexual adventures. Matt and Kris, friends for years, want to have an only-once, no-strings good time. Abby and Andrew, married, celebrate his birthday, but it's marred by angst and miscommunication. Mia and Eric are exes, making sure they are over each other. Jaime and Ken work together and this is a first date. Inez and Gord invite his roommate, Dave, to join them. By the time each couple has gone through a prelude, foreplay, sex, an interlude, orgasm, and afterglow, they've answered basic questions: can sex be anonymous, are we bored, is our marriage really finished, does anyone tell the truth, and how do we make someone happy?

Set in 19th Century Canada, Brigitte and her sister Ginger take refuge in a Traders' Fort which later becomes under siege by some savage werewolves. But when one of the girls is bitten, they have no one to turn to but themselves.

The film tells the story of two good friends who live together, Andrew, an agoraphobic travel agent who works from his home, and Dave, a loser who works in an office where he is treated with contempt. Just when it seems things can't get any worse for the two, the entire world outside of their house disappears and is replaced with an endless white void.

Centres on Canadian animator Ryan Larkin, who in later years lived on skid row in Montreal following a history of drug and alcohol abuse.