In the second season, powerhouse physician Dr. Amy Larsen continues to rebuild her life after eight years of her memory were erased. No longer Chief of Internal Medicine at Westside Hospital, Amy must restart her medical journey as an Intern in the hopes of becoming the doctor she once was. She'll confront hard truths about her missing years, work to repair fractured relationships, and seek to reconcile the person she used to be with the one everyone else has come to know.

A struggling actress and an aspiring playwright pour all of their creative energy into the only paying work they can find: role-playing demonstrations for corporate training seminars. When they book the biggest gig of their careers at a hotel conference, they commence work on their most ambitious production to date.