A failed New York playwright stages a suicide in an attempt to win back her ex, only to wind up in the custody of her gambling-addict mother.

Riyo, an orphaned 17-year old, sails from Yokohama to Hawaii in 1918 to marry Matsuji, a man she has never met. Hoping to escape a troubled past and start anew, Riyo is bitterly disappointed upon her arrival: her husband is twice her age. The miserable girl finds solace with her new friend Kana, a young mother who helps Riyo accept her new life.

In the future, an outbreak of canine flu leads the mayor of a Japanese city to banish all dogs to an island used as a garbage dump. The outcasts must soon embark on an epic journey when a 12-year-old boy arrives on the island to find his beloved pet.