Dr. Bill Cortner and his fiancée, Jan Compton, are driving to his lab when they get into a horrible car accident. Compton is decapitated. But Cortner is not fazed by this seemingly insurmountable hurdle. His expertise is in transplants, and he is excited to perform the first head transplant. Keeping Compton's head alive in his lab, Cortner plans the groundbreaking yet unorthodox surgery. First, however, he needs a body.

Dr. Bill Cortner and his fiancée, Jan Compton, are driving to his lab when they get into a horrible car accident. Compton is decapitated. But Cortner is not fazed by this seemingly insurmountable hurdle. His expertise is in transplants, and he is excited to perform the first head transplant. Keeping Compton's head alive in his lab, Cortner plans the groundbreaking yet unorthodox surgery. First, however, he needs a body.

流行女歌手叶室千枝子（路加奈子 饰）和青年画家仓桥（石浜朗 饰）一同来看牙医。诊所的肃穆气氛让千枝子愈加紧张害怕，而她的紧张情绪也影响到了仓桥。在将二人麻醉之后，牙医（花川蝶十郎 饰）和护士（松井康子 饰）露出了狰狞的面目，千枝子和仓桥也由此进入一个亦真亦幻的诡异世界……
根据日本魔鬼派作家谷崎润一郎1926年同名短篇小说改编，影片被标榜为日本第一部“粉红电影”，也是首部遭到“喷雾”命运的影片。