When the double wedding takes two daughters away from the old man at once, the youngest, now the only one left, in outraged spirit promises never to leave her father, but soon she too is departing for a new home. Then comes a cold hard fact of life. The son-in-law claims his right to make a home alone for his wife. In his bitterness and anger, the father denies them both the house. Several years later the lonely old man meets at the gate a babe in arms. When he learns whose baby it is, heart hunger craves another sight, and sought, brings with it the only natural result.

An elderly carpenter is told by a doctor that his wife is seriously ill. Soon afterwards, an insensitive shop foreman lays him off from his job because of his age. Unable to find work, and with his wife's condition getting worse, he soon becomes desperate.

A young woman's peaceful existence is shattered when she is abducted by the crew of a boat of smugglers, who then also turn against their captain.

A wagon train heading west across the great desert runs out of water, and is attacked by Indians. One man -- their last hope -- is sent out to find water.

A wealthy, callous moneylender finds a terrifying way to learn about money's limitations.

In Bagdad, Princess Badr al-Budur, the daughter of the Sultan, falls in love with Aladdin, the son of a poor tailor, and rejects the suit of evil alchemist al-Talib, her father's choice. Al-Talib consults his Evil Spirit, who advises him to find the magic lamp hidden in an underground cave. Unable to get it himself, al-Talib hires Aladdin, who secures the lamp but keeps it when he realizes al-Talib's wickedness. With wealth obtained through wishes, Aladdin courts the princess. After the lamp changes hands between al-Talib and Aladdin, al-Talib steals it and abducts the princess to the desert. Aladdin follows with only a gourd of water. Suffering from thirst and exhaustion, Aladdin nearly succumbs, but the horsemen of the Sultan, who learned of his daughter's abduction, ride up and rescue Aladdin.

A father, anxious for his son's financial well being, develops a special soda pop called Dopokoke which is laced with cocaine. Dopokoke is advertised as relief "for that tired feeling." The drink is a success, but the son becomes addicted to it, much to his father's regret. Loosely based on the allegations that the Coca-Cola company and other soft drink manufacturers laced their soda with dope.

After the relatively low box office takings of 'Intolerance', D. W. Griffith would revisit his epic film three years later by releasing two of the film's interlocking stories as standalone features, with some new additional footage. The first of the two was 'The Fall of Babylon', which depicts the conflict between Prince Belshazzar of Babylon and Cyrus the Great of Persia.