The "Missing Heart Murders" are plaguing San Francisco - dead bodies that turn up with their hears surgically removed! So a weak-stomached homicide cop looks into the possibilities of a black market for human organs, while across town a man must make a difficult decision regarding his wife, who needs a transplant...

While searching for a small fortune of embezzled money, an ex-con, a small-time bandleader, his doting wife and a kooky drifter find themselves being followed. Their chase takes them to trailer camps, bingo halls, laundromats and ultimately, a showdown with a group of unconventional bad guys.