A mysterious virus spreads out. Anyone infected feels the emotion of love, and the emotion amplifies until it kills the person in love. The pessimist Taek-seon, who likes nothing in life, is infected, and the researcher Gyun reaches her out to test her the medicine that he's developing. Soon Gyun finds out Taek-seon has special antibody, but Taek-seon slowly feels love to Gyun. Is this a real love or just a virus?

该剧讲述想要恋爱也想避开错的人的徐至星（宋昰昀 饰）制造了“祖上神”一样的AI冰箱，她研发的AI系统可以分辨出垃圾一样的人，由此展开了浪漫爱情喜剧。
李濬荣饰演“祖上神”唯一无法分辨的消防员郑国锡，是不会使用电子媒体产品的始终如一的男人。