In the future, humans are divided into Sex Negatives and Sex Positives. The negatives get sick if they have sex so they go to Cafe Flesh to see positives who are forced to perform on stage for the negatives. Lana is a positive who everyone thinks is a negative and she must decide whether to come clean or not.

Mrs. Van Houten has shown signs of losing touch with reality, and her husband discusses possible treatment with Dr. Caligari, who says Mrs. Van Houten has a disease of the libido.