An ambitious and insensitive tabloid crime photographer falls victim to a mysterious illness that makes him lose, one by one, his five senses.

Mexico at the beginning of the 20th century: one night the monks of the San Francisco Abbey find a baby in front of their gate. They call the boy Marcelino and take care of the little one with devotion...

In the abandoned town of La Estancia, bound by time and space, an unusual relationship develops between one of the last inhabitants, Juan Diego and the filmmaker documenting his life.