该剧讲述了一个温良贤淑的柔弱少妇成长为独立坚强的都市女性的蜕变历程。温柔贤淑的沈静雅与陈振海结婚五年，因婚后琐碎的家务活，让昔日美丽动人的沈静雅渐渐迷失自我，她变得体态臃肿，满脸雀斑。平淡的婚姻生活逐渐让陈振海厌倦。此刻陈振海的邻家小妹李曼丽留美归国。
五年前，李曼丽就爱上陈振海，却因陈振海已娶沈静雅为妻，怅然若失的李曼丽远走美国。五年后，李曼丽回国，跟陈振海发生一段不伦情分享者影视。沈静雅知晓后，尽管伤心欲绝，但她还是多次试图挽回婚姻，但终究徒劳无功。沈静雅跟陈振海离婚后，沈静雅万念俱灰，决定抛弃过去，重新振作并努力学习，改头换面变成了一个新时代女性的励志故事。

姚七星（方中信 饰）和抽水强（森美 饰）被指派对付绑匪杀人王，经过一番激烈的枪战，杀人王重伤不治。临死前，愤怒的杀人王放出话来，说做鬼也不会放过姚七星。姚七星的血液里流淌着特殊的基因，身为家中老七，他竟然得到了能够看到鬼魂的阴阳眼。
一次偶然中，姚七星看到了被杀人王所害的好友，好友告诉姚七星，杀人王将会在头七之日从阴曹地府回来找他报仇，这让姚七星感到十分害怕。上司Madam徐（梁敏仪 饰）派遣姚七星和抽水强前往七号差馆处理文件，在那里，姚七星遇见了灵异顾问喃呒炳（元华 饰），这位经验丰富的顾问成为了姚七星最后一根救命稻草。

Fanny is a skilled mahjong player and young housewife, who's usually forbidden from her tile-clicking addiction by husband Johnny. However, when Johnny falls in with gambler Demon, Fanny gets sent packing. Johnny takes up with Demon's sister Curvy, and Fanny is left alone and seems to lose her mahjong-playing skills. Luckily, she receives additional training from her mahjong mentor Three Tiles, who also schooled Auntie Fei, as well as sexy player-in-training First Love. With the aid of her mahjong sisters, brother, plus Auntie Fei's husband Chi Mo Sai, Fanny regroups in time to take on Curvy, Demon, and Johnny at a climactic mahjong tournament.