Ryan and Jennifer are opposites who definitely do not attract. At least that's what they always believed. When they met as twelve-year-olds, they disliked one another. When they met again as teenagers, they loathed each other. But when they meet in college, the uptight Ryan and the free-spirited Jennifer find that their differences bind them together and a rare friendship develops.

国际刑警赛门，调查黑市武器弹药案时，不巧的介入一名CIA探员尼克所处理的绑票案。这名被绑架的富家女跟赛门调查的案子有关联吗？

The film tells the story of two good friends who live together, Andrew, an agoraphobic travel agent who works from his home, and Dave, a loser who works in an office where he is treated with contempt. Just when it seems things can't get any worse for the two, the entire world outside of their house disappears and is replaced with an endless white void.