Hua Mujin grew up during the chaotic era of the five dynasties and the ten states. As a child, she and her younger twin sister Hua Jinxiu were sold as slaves to the powerful Yuan Family. They are sent on the road with three other children - Yu Feiyan, Song Minglei, Yao Biying and the five take a vow of friendship to always care for each other.

凡间百姓若遇坎坷离合会去求神拜佛，可若是神仙呢？该剧讲述了上古界四位真神中白玦与上古之间几经生死离别的情深虐恋。以上古的成长为主线，从灵力低微的小“菜鸟”成长为身负苍生之重的主神，却终究逃不过命运的劫难枷锁。
神生长远，情根深种，有人为了她不惜毁天灭地，即使三界化为虚有也在所不惜，有人默默等待了六万年，用自己还给她三界永生。
九州八荒之下，她又是否能够承载这一场超越三生三世的亘古之恋？