六个青春男女：泰勒（Terry Erioski 饰）、丹娜（Jessica Custodio 饰）、伊基（Zak Kilberg 饰）、海瑟尔（Laura Bach 饰）、雷兹（Billy Beck 饰）和布莱登（Travis Wood 饰）受雇来到一所废弃的大房子内作打扫。他们白天拼命工作，夜晚纵情狂欢。他们的玩乐很快超出了底线，这群青年在后院发现了一个古代的墓碑和一本古书。好奇心促使他们翻开了这本书，却无意中释放了古代Cthulhu教派所信奉的邪恶女魔鬼。
关于这间房屋的过往逐渐浮出水面，而年轻人们面对的则是一个似乎永无止境的恐怖屠杀夜……

After accidentally knocking her best friend off a roof, Alyce is haunted by guilt and delves into a brutal nightmare wonderland of sex, drugs and violence, her mind tearing itself apart… along with anyone else who gets in her way.

A newly reunited young couple's drive through the Pacific Northwest turns into a nightmare as they are forced to face nature, unsavory locals, and a monstrous creature, known to the Native Americans as Oh-Mah.

In the not too distant future a secret government re-animation chemo-virus gets released into conservative Sartre, Nebraska and lands in an underground strip club. As the virus begins to spread, turning the strippers into "Super Zombie Strippers" the girls struggle with whether or not to conform to the new "fad" even if it means there's no turning back.