Ride with the Devil follows four people who are fighting for truth and justice amidst the turmoil of the American Civil War. Director Ang Lee takes us to a no man's land on the Missouri/Kansas border where a staunch loyalist, an immigrant's son, a freed slave, and a young widow form an unlikely friendship as they learn how to survive in an uncertain time. In a place without rules and redefine the meaning of bravery and honor.

李安继《少年派的奇幻漂流》之后的又一部3D电影，电影有如“上世纪六七十年代拳击界的史诗”，将透视出那个年代众多卓越的拳手和著名的拳赛，向上个世纪六七十年代众多卓越的拳手和著名的拳赛致敬。剧中的重头戏是前世界重量级拳王乔·弗雷泽与阿里之间那场被称为“马尼拉式震撼”的传奇之战。