The privileged prep school teens on Manhattan’s Upper East Side first learn that notorious party girl Serena Van Der Woodsen is back in town the way they learn all the important news in their lives–from the blog of the all-knowing albeit ultra-secretive Gossip Girl. Serena’s closest friend, Blair, is just as surprised as everyone else to find that Serena has suddenly ended her self-imposed exile to boarding school and returned to Manhattan. The tension between Blair and Serena isn’t lost on Gossip Girl, who is determined to uncover and fuel any and all scandals. Does it involve Serena’s younger brother Eric, Blair’s boyfriend Nate or Nate’s buddy Chuck? Maybe it has something to do with Dan and his sister Jenny, whose middle-class background keeps them on the fringes of this exclusive clique who live for fashion, shopping and partying–along with gossip.

Greg is coasting through senior year of high school as anonymously as possible, avoiding social interactions like the plague while secretly making spirited, bizarre films with Earl, his only friend. But both his anonymity and friendship threaten to unravel when his mother forces him to befriend a classmate with leukemia.

When Juli meets Bryce in the second grade, she knows it's true love. After spending six years trying to convince Bryce the same, she's ready to give up - until he starts to reconsider.

One student dead, another student missing, and the kids get framed when the headmaster's search turns up ecstasy among their possessions.