In 1926, Newt Scamander arrives at the Magical Congress of the United States of America with a magically expanded briefcase, which houses a number of dangerous creatures and their habitats. When the creatures escape from the briefcase, it sends the American wizarding authorities after Newt, and threatens to strain even further the state of magical and non-magical relations.

In a suburban fantasy world, two teenage elf brothers embark on an extraordinary quest to discover if there is still a little magic left out there.

After a strange dream of a mysterious ancestor, high school student Yuuko Yoshida wakes to see that she has grown demonic horns and a tail. Dazed and confused, her mother reveals to her a dark family secret: her family is descended from a Dark Clan that was banished to live powerless and destitute by their mortal enemies, the magical girls of the Light Clan. The only way to lift their ancestry's curse is for Yuuko to find a magical girl, murder her, and splatter her blood all over her ancestor's Demon God statue.

Fortunately for "Shadow Mistress Yuuko," a magical girl saves her from being run over by an oncoming truck. Unfortunately, Momo Chiyoda happens to be Yuuko's classmate at Sakuragaoka High and is much stronger than her in both strength and endurance. Taking pity on her wimpy assailant, the magical girl agrees to train Yuuko and help her unlock her dormant powers. Now, Yuuko must rise up and defeat her generous frenemy to save her family from the terrible grip of poverty.

梅莉达（楠木灯 配音）出生于大名鼎鼎的豪门“圣骑士”家族，每一位拥有圣骑士血统的亲眷们都能够使用非常强大的能力。可是，这样的能力在梅莉达的身上却全无踪迹，梅莉达因为被怀疑血统并不纯正而遭到了流放，可即便如此，勤劳坚韧的梅莉达还是对每日的修行毫不松懈，坚信自己总有一天能够爆发出令旁人震惊的力量。
库法（小野友树 配音）被排遣到梅莉达的身边成为了她的家庭教师，实际上，库法的真实身份是隶属于白夜骑兵团的杀手。上级命令库法接近梅莉达，一旦确认她确实无法使用能力后，即将她暗杀。然而，梅莉达的乐观和坚持渐渐打动了库法。

和风吹拂的美丽大地·阿斯特雷亚大陆。
在大陆的一角，失去记忆的少年·佑树醒了过来。
照顾他的小小向导·可可萝。
总是肚子空空的美少女剑士·佩可莉露。
略显高冷的猫耳魔法少女·凯露。
他们就这么在命运引导下，建立起名为「美食殿」的公会。
现在，佑树与她们的冒险即将开幕——

能干的程序员，同时是重度机器人宅的青年，转生到了巨大机器人“幻晶骑士（Silhouette Knight）”震动大地的骑士与魔法的异世界！？
以艾尔涅斯帝·埃切贝里亚的身份转生的他，活用丰富的机械知识以及身为程序员的才能，开始制造理想的机器人。但，他的行动演变成了超出预期的事态……！？
机器人宅的野望，将改变异世界！！

故事发生在一块充满魔力的土地上。在这个人人都有魔法的家族，唯一的普通女孩将迎接怎样的挑战？