《开心公寓》以上海文艺频道知名主持人为演员主体，以一家酒店式公寓为载体，以反应更广泛更深刻的社会百态为内容，注重时尚化、现代感，表现了新上海新白领的城市生活。
《开心公寓》从开播伊始就取得了相当高的收视率，可以说是风靡了上海的“白领一族”，相对于海派情景喜剧的领头羊《老娘舅》来说，显得更青春，更具有活力。它轻快的节奏，幽默的语言，和时尚的表现方式，拓展了海派情景喜剧的外沿和内涵，成为“新上海情景喜剧”发展的风向标。

In 2071, roughly fifty years after an accident with a hyperspace gateway made the Earth almost uninhabitable, humanity has colonized most of the rocky planets and moons of the Solar System. Amid a rising crime rate, the Inter Solar System Police (ISSP) set up a legalized contract system, in which registered bounty hunters, also referred to as "Cowboys", chase criminals and bring them in alive in return for a reward.