Bourne is brought out of hiding once again by reporter Simon Ross who is trying to unveil Operation Blackbriar, an upgrade to Project Treadstone, in a series of newspaper columns. Information from the reporter stirs a new set of memories, and Bourne must finally uncover his dark past while dodging The Company's best efforts to eradicate him.

After seeking to live a normal life, Logan sets out to avenge the death of his girlfriend by undergoing the mutant Weapon X program and becoming Wolverine.