When a cure is found to treat mutations, lines are drawn amongst the X-Men—led by Professor Charles Xavier—and the Brotherhood, a band of powerful mutants organised under Xavier's former ally, Magneto.

Professor Charles Xavier and his team of genetically gifted superheroes face a rising tide of anti-mutant sentiment led by Col. William Stryker. Storm, Wolverine and Jean Grey must join their usual nemeses—Magneto and Mystique—to unhinge Stryker's scheme to exterminate all mutants.

Before Charles Xavier and Erik Lensherr took the names Professor X and Magneto, they were two young men discovering their powers for the first time. Before they were arch-enemies, they were closest of friends, working together with other mutants (some familiar, some new), to stop the greatest threat the world has ever known.

After seeking to live a normal life, Logan sets out to avenge the death of his girlfriend by undergoing the mutant Weapon X program and becoming Wolverine.

The ultimate X-Men ensemble fights a war for the survival of the species across two time periods as they join forces with their younger selves in an epic battle that must change the past – to save our future.

Peter Parker is an outcast high schooler abandoned by his parents as a boy, leaving him to be raised by his Uncle Ben and Aunt May. Like most teenagers, Peter is trying to figure out who he is and how he got to be the person he is today. As Peter discovers a mysterious briefcase that belonged to his father, he begins a quest to understand his parents' disappearance – leading him directly to Oscorp and the lab of Dr. Curt Connors, his father's former partner. As Spider-Man is set on a collision course with Connors' alter ego, The Lizard, Peter will make life-altering choices to use his powers and shape his destiny to become a hero.

Following the death of District Attorney Harvey Dent, Batman assumes responsibility for Dent's crimes to protect the late attorney's reputation and is subsequently hunted by the Gotham City Police Department. Eight years later, Batman encounters the mysterious Selina Kyle and the villainous Bane, a new terrorist leader who overwhelms Gotham's finest. The Dark Knight resurfaces to protect a city that has branded him an enemy.