米克（杰森·雷特 Jason Ritter 饰）和查理（杰西·艾森伯格 Jesse Eisenberg 饰）是曾在同一所高中就读的校友，如今，双双毕业的两人升上了同一所大学。在学校里，查理邂逅了名为玛丽（伊娃·阿穆里 Eva Amurri 饰）的女生，后者的美丽的温柔让查理很快就坠入了情网。
然而，随着时间的推移，查理发现玛丽对桀骜不驯痞里痞气的米克似乎更感兴趣一些，不仅如此，查理的朋友们也接二连三的站在了米克的那一边。查理相信，这一切并非偶然，深藏不露的米克一定正在筹划一场复仇，而复仇的原因，来自于他们两人深深隐藏在心底的一个秘密。如果将这个秘密放置不管，所有的一切一定会慢慢发酵成为无法挽回的悲剧。

Some Boys Don't Leave is the story of what happens when the break-up happens but the break does not. 'Boy' is forced to come to terms with the fact that 'Girl' no longer wants him around. The only problem is he just can't seem to leave their once shared apartment. 'Girl' decides to keep living her life around him; while he remains, watching at a distance. In time, each decides to go in his or her own distinctly different directions. 'Boy' soon finds that sometimes the greatest distance we are asked to travel is one within ourselves.