A likeable, married high school teacher spirals out of control when a student in his class begins unintentionally reminding him of his doomed first love, which ended 17 years earlier.

年少时便失去父亲的武成（安在旭 饰），不久连母亲都离开了他。他的职业是一名医生，心灵上的创伤连自己都无法医治。
孤儿英珠（李恩珠 饰）是一名专业化妆师，命途多舛的她如今被诊断为胃癌晚期，她的生活充满了折磨的疼痛感，辛酸不已。
两人在缘分的牵引下，相识于情侣酒店。同病相怜的两人向对方倾吐心声，很快便相恋了。英珠的疾病与死神的到来将为他们的恋情带来险阻，他们更爱彼此了，两人深信属于他们的爱情能永存。

Kyung-woo自小就有视障问题，所以对UFO感到好奇的她永远不能看见自己想见的东西。在辅导中心工作的她因为夜归，每晚都乘搭尾班巴士回家。而驾驶这尾班巴士的便是PARKSang-hyun。
失恋过的Sang-hyun日间是一名巴士司机，但放工后便在自己的家仿如电台唱片骑师般主持节目。有时他会因独自主持节目而感到寂寞。Sang-hyun和Kyung-woo本来并不相识，然而某一晚Kyung-woo坐巴士坐到总站仍未下车，Sang-hyun便上前唤醒她……

A cop's desire for love gets in the way of his job and his professional life. Secret love affairs begin to dangerously collide as he gets assigned to a new homicide case.

When filmmaker Young-soo introduces writer Soo-jung to his friend Jae-hoon, he unintentionally creates a love triangle. While Jae-hoon pursues Soo-jung, Young-soo clashes with his crew. Yet, just as the story appears to end, it starts all over again, this time with plenty of variations.