格雷德（任达华 饰）是一位医术十分精湛的医生，他将全部的精力都投入到了新药的研发当中去，希望能够制造一种治疗百病使人身强体健的新药。在教授的支持下，格雷德的研究十分顺利，然而很快格雷德便发现，教授竟然企图窃取他的研究成果。一场意外之中，教授不幸身亡，格雷德失去了经济上的支持，研究无法继续，只能和女友一同回到香港。
在国内，医学委员会委员迈克（郑浩南 饰）十分赏识格雷德，给予了他大力的支持，哪知道背地里，道貌岸然的迈克竟然打起了格雷德女友的主意，并趁其不备将其玷污。之后，女友决定和格雷德联起手来报复迈克，格雷德更是将尚未实验的新药用在了迈克的身上。

A reporter and the producer of "Horror Hotline", a popular radio call-in show, investigate a caller's tale about a terrifying mutant infant that caused several deaths in the 1960s and seems to be making people disappear today.

As children, the introverted Smile was being bullied by a gang of kids until the brash Peco comes by and chases all of them them away. Peco then takes Smile under his wings and teaches him how to play the game of ping pong. From there a life long best friend relationship comes into existence between these two polar opposite kids.

A man develops a relationship with a woman who has mysterious supernatural abilities.