It is the year 2808. Three convicts are recruited as members of the Cyber Police to keep major criminal activity in Oedo (formerly Tokyo) in check. In return, their life sentences will be reduced by a few years for every mission accomplished. However, to ensure that these convicts are doing their job, the police have secured special collars around their necks. If they attempt to remove their collars or fail to meet the time limit of their mission, the collars will self-destruct.

044(forty.four)是藉由通过病毒在操作遗传因子从而获得超群的战斗力的最强的女战士。但是作为这种力量的代价，她的寿命也被缩短至仅剩一点。她接到政府给予的任务，歼灭吸血鬼军团“phage”以及他们的首领“king”的命令。但是，044在这场战斗中和年轻的phage战士卢卡相遇了，不知为什么044不能对卢卡痛下杀手。就在044扪心自问时，结果却被政府那边的统领“达克萨斯・朱尼亚”视为了背叛者，从而被phage和政府两边同时追杀。受伤的卢卡和044持续着逃亡，但就在这时，他们听到了一个充满慈爱的谜之声。接着，044和卢卡向着最终决战前发起了突击。抱着淡淡的爱意。

2007 film directed by Masayuki Kojima