A depressed musician reunites with his lover in the desolate streets of Detroit. Though their romance has endured several centuries, it is tested by the arrival of her capricious and unpredictable younger sister.

Twenty-eight days after a killer virus was accidentally unleashed from a British research facility, a small group of London survivors are caught in a desperate struggle to protect themselves from the infected. Carried by animals and humans, the virus turns those it infects into homicidal maniacs -- and it's absolutely impossible to contain.