When Rango, a lost family pet, accidentally winds up in the gritty, gun-slinging town of Dirt, the less-than-courageous lizard suddenly finds he stands out. Welcomed as the last hope the town has been waiting for, new Sheriff Rango is forced to play his new role to the hilt.

Wounded Civil War soldier John Dunbar tries to commit suicide—and becomes a hero instead. As a reward, he's assigned to his dream post, a remote junction on the Western frontier, and soon makes unlikely friends with the local Sioux tribe.

In war-torn colonial America, in the midst of a bloody battle between British, the French and Native American allies, the aristocratic daughter of a British Colonel and her party are captured by a group of Huron warriors. Fortunately, a group of three Mohican trappers comes to their rescue.