Video game bad guy Ralph and fellow misfit Vanellope von Schweetz must risk it all by traveling to the World Wide Web in search of a replacement part to save Vanellope's video game, Sugar Rush. In way over their heads, Ralph and Vanellope rely on the citizens of the internet — the netizens — to help navigate their way, including an entrepreneur named Yesss, who is the head algorithm and the heart and soul of trend-making site BuzzzTube.

When the creator of a popular video game system dies, a virtual contest is created to compete for his fortune.

Video game experts are recruited by the military to fight 1980s-era video game characters who've attacked New York.