In the midst of World War 2, a OSS officer leads a group of female pilots on a mission to deliver a secret weapon, only to crash land on an island in the Pacific after an encounter with a deadly storm. On the island, they must not only contend with a small band of Japanese soldiers but the native inhabitants of the island as well - vicious prehistoric Pterodons.

故事发生在2012年12月，一家人正在度假。没想到根据玛雅预言，2012年的12月21日，正是世界末日，玛雅人的日历也到那天为止，再没有下一页。人类要如何才能阻止一切被毁灭呢？

James Murphey is a rugged cryptozoologist, who thirty years earlier, during a trip to Loch Ness, Scotland, had a fatal encounter with the fabled "Nessie" creature that killed his father, and left James with deep facial scar. Twenty years later, James is hunting for Nessie, when his search leads him to the sleepy town of Pike Island, Ashburn, on Lake Superior. Hiring Josh Riley as his guide, James and Josh bond over their mutual scientific interests and deceased fathers, while James tries to convince Josh's mother, Sheriff Karen Riley, that the 60-foot plesiosaur is killing and breeding.