A mysterious new priest comes to town to stay with fellow men of the cloth Erik Estrada, and Jan-Michael Vincent. Little do they know, this ferocious father possesses extraordinary martial arts skill, crucifix blades and a gold handgun with the cross on the handle. Soon, in this "bad" neighborhood, the priest begins cleaning up the local drug dealing scum-bags. Then he meets lunatic Don Stroud in the confessional, and Stroud claims to be the bloodsucking, skull stealing "vampire" serial killer ravaging the city. The priest encounters a young lass who has visions of Stroud committing his dastardly deeds, and when the vampire kidnaps her the priest speaks the words, "Open the gates of Hell! For I am the right hand of God!!!," and sets off towards his deadliest encounter yet.

In the year of 2008, war and sickness have overtaken the planet. The deranged government declares single women a threat to the human race. Singles women are imprisoned. The corrupt warden is determined to keep the prisoners locked up.