Simón is the owner of a hardware store in the greater Buenos Aires area with four employees. Constantly mistreating them, he never gives them a break, creating a high level of unease in the everyday work routine. Absolutely submerged into the world of labor, The Spider's Lullaby weaves its story with each tension that shape management authoritarianism but also solidarity, resistance, and vile deeds among colleagues.

Some kidnappers kidnap a wealthy young woman and the one who should pay the ransom has mysteriously disappeared. While they look for it, inexplicable events begin to occur that will force them to fight against their worst fears to survive.