在内布拉斯加州的一个小镇上，一个患有精神病的12岁女孩招募了其他所有孩子，并进行了血腥的暴行，杀死了腐败的成年人和其他反对她的人。一个聪明的高中生不同意这个计划，他是这个小镇唯一生存的希望。

After a nuclear war decimated the northern hemisphere, the surviving population in the south become desperate and violent competing for scarce resources. Society crumbles and an infectious bacteria threatens to destroy those who remain. In an attempt to rebuild civilization, a self appointed government called 'The ORDER' distributed an immunization to the bacteria, via a massive Electro-Macnetic Pulse (EMP). Secretly, the Order also delivered a bio-tech virus through the EMP, giving them the power to control the population. One man remains immune to the Order's virus - Jake Slater. Now Jake scavenges the wasteland searching for a way to keep his unconscious daughter alive, unaware she is the last child on Earth, and the key to the survival of mankind.