Timothy (Dickie Moore), an orphan, is sent with his sister, Gay (Sally Martin), to a farm run by Vilda Cummins (Elizabeth Patterson, an old maid with a dislike for children. Timothy eventually wins her over, and also pushes along the romance for her niece, Martha (Eleanore Whitney), with David Masters (Tom Keene).

Rose Pierce is discontent with her life as the wife of a small town plumber and has visions of becoming a wealthy socialite. Consequently, when her smart aleck son Sammy hears that an electric railroad line is to be built through town, she decides that the family can become rich by purchasing the lots along the right of way. Patriarch George Pierce laughs at the idea, but when Rose and Sammy learn that Cora Stewart, the wealthy town widow, has withdrawn her savings from the bank, they jump to the conclusion that she is interested in buying the lots, and mother and son secretly invest the family bank roll in the land.

A man wins $50,000 in a card game with gamblers, but is soon found dead and the money missing. Slip and Sach find the money near where the body was discovered, and soon find themselves the target of both the police and the gamblers.

An elderly schoolmarm makes a hit in New York after a bandleader jazzes up her corny song.

The East Side boxing champion Muggs answers a challenge to a fight against the West Side champ but just before the match he is kidnapped. His friend Danny Lyons takes his place and wins the fight, only to have Mugs believe that Danny was responsible for his kidnapping.

Slip and the gang stray from newspaper work to detective work.

Womanizer and airline pilot Jack Gordon must fly the world's fastest airliner from New York to California while dealing with dangerous jewel thieves on the run from the law.

The boys get mixed up with a race horse & crooked gamblers

While working in a laundromat, the boys find a baby hidden among the linen. They soon find out that the baby, who is the heir to a fortune, has been abandoned by his mother so that her two evil aunts can't cheat her and the baby out of the inheritance. The boys determine to help the woman claim her baby's rightful inheritance from her aunts, who have hired gangsters to find and eliminate the girl, the baby and anyone who helps them.

Slip, Sach and the rest of the Bowery Boys enter a haunted house, where they engage in slapstick with a gorilla, a robot and a vampire

A Capone-like racketeer named Anderson, who after being chased out of one town by the authorities immediately sets up shop in another. Unable to get any tangible evidence against Anderson, DA Wayne orders his assistant Carter to dig up some dirt on the gangster boss. To do this, Carter pretends to turned crooked, joining Anderson's gang in order to accumulate evidence. Alas, Carter's girl friend Patricia knows nothing of her boyfriend's subterfuge, and she suspects the worst.