In the harsh, wintry woods of rural Quebec, Bruce (Thomas Haden Church), a down-on-his-luck snowplow operator, accidentally kills a man during a drunken night joyride. Stricken with panic, he hides the body and takes to the deep wilderness in hopes of outrunning both the authorities and his own conscience. But as both begin to close in, Bruce falls apart mentally and morally and mysteries unravel to reveal who he was before the accident, the truth behind his victim, and the circumstances that brought them together in a single moment.

天性与后天的培养究竟哪个更重要？本·莫林和妻子凯瑟琳·奥尼尔都是备受尊敬的科学家，两人进行了一项他们认为能改变人类对自己身份认知的实验：用与三个孩子遗传的天性相悖的方式抚养他们，最终证明后天对孩子的抚养可以胜过孩子先天的天性。他们希望证明人都具备达成任何成就的潜能。本和凯瑟琳在实验中发现了家庭的可贵，比起实验的科学真相，后者微不足道。